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Extracellular Vesicles in Bile as Markers of Malignant Biliary Stenoses

Delhaye, Myriam
Published in Gastroenterology. 2017, vol. 153, no. 2, p. 495-504.e8
Abstract Algorithms for diagnosis of malignant common bile duct (CBD) stenoses are complex and lack accuracy. Malignant tumors secrete large numbers of extracellular vesicles (EVs) into surrounding fluids; EVs might therefore serve as biomarkers for diagnosis. We investigated whether concentrations of EVs in bile could discriminate malignant from nonmalignant CBD stenoses.
Keywords AdultAgedAged, 80 and overBileBile Duct Neoplasms/complications/diagnosisBiomarkers, Tumor/analysisCholangiocarcinoma/complications/diagnosisCholestasis/diagnosis/etiologyEuropeExtracellular VesiclesFemaleGallstones/diagnosisHumansMaleMiddle AgedPancreatic Neoplasms/complications/diagnosisPancreatitis, Chronic/complications/diagnosisProspective StudiesROC Curve
PMID: 28479376
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Research groups Analyse protéomique et Analyse génomique des maladies rénales (659)
Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
Physiopathologie de la pancréatite aiguë (601)
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SEVERINO, Valeria et al. Extracellular Vesicles in Bile as Markers of Malignant Biliary Stenoses. In: Gastroenterology, 2017, vol. 153, n° 2, p. 495-504.e8. doi: 10.1053/j.gastro.2017.04.043 https://archive-ouverte.unige.ch/unige:98391

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Deposited on : 2017-11-01

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