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Title

Extracellular Vesicles in Bile as Markers of Malignant Biliary Stenoses

Authors
Delhaye, Myriam
Published in Gastroenterology. 2017, vol. 153, no. 2, p. 495-504.e8
Abstract Algorithms for diagnosis of malignant common bile duct (CBD) stenoses are complex and lack accuracy. Malignant tumors secrete large numbers of extracellular vesicles (EVs) into surrounding fluids; EVs might therefore serve as biomarkers for diagnosis. We investigated whether concentrations of EVs in bile could discriminate malignant from nonmalignant CBD stenoses.
Keywords AdultAgedAged, 80 and overBileBile Duct Neoplasms/complications/diagnosisBiomarkers, Tumor/analysisCholangiocarcinoma/complications/diagnosisCholestasis/diagnosis/etiologyEuropeExtracellular VesiclesFemaleGallstones/diagnosisHumansMaleMiddle AgedPancreatic Neoplasms/complications/diagnosisPancreatitis, Chronic/complications/diagnosisProspective StudiesROC Curve
Identifiers
PMID: 28479376
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Structures
Research groups Analyse protéomique et Analyse génomique des maladies rénales (659)
Physiopathologie de la pancréatite aiguë (601)
Chirurgie viscérale (104)
Citation
(ISO format)
SEVERINO, Valeria et al. Extracellular Vesicles in Bile as Markers of Malignant Biliary Stenoses. In: Gastroenterology, 2017, vol. 153, n° 2, p. 495-504.e8. https://archive-ouverte.unige.ch/unige:98391

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Deposited on : 2017-11-01

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