Epilepsy due to an autoimmune disease is a recently recognized entity. Among the best-known diseases are paraneoplastic limbic encephalitis, limbic encephalitis associated with voltage-gated potassium channels (VGKC)) antibody glutamic acid decarboxylase antacid, antireceptor antibodies N-methyl-D-aspartate, Rasmussen and Hashimoto encephalitis. More efficient imaging technics and immunologic laboratory analyses have allowed us to deepen our knowledge concerning these diseases that are most common in adults. In this article we will describe the most common imagery findings and the most appropriate methods of image analysis.