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Surface-modified silicone foils for intraocular implantation

Fischer, Sarah
Carstesen, Dörthe
Klee, Doris
Walter, Peter
Published in Graefe's Archive for Clinical and Experimental Ophthalmology. 2012, vol. 250, no. 6, p. 823-827
Abstract Implantation of silicone materials like iris diaphragms into the eye can be complicated by cell migration and attachment. We studied polydimethylsiloxane (PDMS) foils coated with isocyanate terminated, star-shaped poly(ethylene glycol-stat-propylene glycol) (NCO-sP(EO-stat-PO)) equipped with heparin towards the inhibition of cell attachment without influencing cell viability.
Keywords AnimalsApoptosisArtificial OrgansCell Adhesion/physiologyCell ProliferationCell Survival/physiologyCells, CulturedCoated Materials, BiocompatibleDimethylpolysiloxanesFibroblasts/cytologyHeparinIrisMaterials TestingMicePolyethylene GlycolsPropylene Glycol
PMID: 22354368
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FISCHER, Sarah et al. Surface-modified silicone foils for intraocular implantation. In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2012, vol. 250, n° 6, p. 823-827. doi: 10.1007/s00417-012-1956-1

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Deposited on : 2017-09-15

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