Surface-modified silicone foils for intraocular implantation

Fischer, Sarah; Carstesen, Dörthe; Klee, Doris; Walter, Peter; Weinberger, Andreas

doi:10.1007/s00417-012-1956-1

Scientific article

English

Surface-modified silicone foils for intraocular implantation

ContributorsFischer, Sarah; Carstesen, Dörthe; Klee, Doris; Walter, Peter; Weinberger, Andreas

Published inGraefe's Archive for Clinical and Experimental Ophthalmology, vol. 250, no. 6, p. 823-827

Publication date2012

Abstract

Implantation of silicone materials like iris diaphragms into the eye can be complicated by cell migration and attachment. We studied polydimethylsiloxane (PDMS) foils coated with isocyanate terminated, star-shaped poly(ethylene glycol-stat-propylene glycol) (NCO-sP(EO-stat-PO)) equipped with heparin towards the inhibition of cell attachment without influencing cell viability.

Keywords

Animals
Apoptosis
Artificial Organs
Cell Adhesion/physiology
Cell Proliferation
Cell Survival/physiology
Cells, Cultured
Coated Materials, Biocompatible
Dimethylpolysiloxanes
Fibroblasts/cytology
Heparin
Iris
Materials Testing
Mice
Polyethylene Glycols
Propylene Glycol

Affiliation entities

Not a UNIGE publication

Citation (ISO format)

FISCHER, Sarah et al. Surface-modified silicone foils for intraocular implantation. In: Graefe’s Archive for Clinical and Experimental Ophthalmology, 2012, vol. 250, n° 6, p. 823–827. doi: 10.1007/s00417-012-1956-1

Article (Published version)

Identifiers

PID : unige:96812
DOI : 10.1007/s00417-012-1956-1
PMID : 22354368

Journal ISSN0721-832X

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Surface-modified silicone foils for intraocular implantation

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