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Title

Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial

Authors
Steinhorn, Robin H
Fineman, Jeffrey
Kusic-Pajic, Andjela
Cornelisse, Peter
Gehin, Martine
Nowbakht, Pegah
Pierce, Christine M
Collaboration
Published in Journal of Pediatrics. 2016, vol. 177, p. 90-96.e3
Abstract To evaluate the efficacy, safety, and pharmacokinetics of the endothelin receptor antagonist bosentan as adjunctive therapy for neonates with persistent pulmonary hypertension of the newborn (PPHN).
Keywords Double-Blind MethodEndothelin Receptor Antagonists/adverse effects/therapeutic useFemaleHumansInfantNewbornMaleNitric Oxide/administration & dosagePersistent Fetal Circulation Syndrome/drug therapyRespirationArtificialSulfonamides/adverse effects/therapeutic useTreatment FailureTreatment Outcome
Identifiers
PMID: 27502103
Full text
Article (Published version) (914 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group L'hypertension pulmonaire (pédiatrie) (228)
Citation
(ISO format)
STEINHORN, Robin H et al. Bosentan as Adjunctive Therapy for Persistent Pulmonary Hypertension of the Newborn: Results of the Randomized Multicenter Placebo-Controlled Exploratory Trial. In: Journal of Pediatrics, 2016, vol. 177, p. 90-96.e3. https://archive-ouverte.unige.ch/unige:96725

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Deposited on : 2017-09-14

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