Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry

Douwes, Johannes M; Humpl, Tilman; Bonnet, Damien; Beghetti, Maurice; Ivy, D Dunbar; Berger, Rolf M F

doi:10.1016/j.jacc.2016.01.015

Scientific article

English

Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry

ContributorsDouwes, Johannes M; Humpl, Tilman; Bonnet, Damien; Beghetti, Maurice; Ivy, D Dunbar; Berger, Rolf M F

Published inJournal of the American College of Cardiology, vol. 67, no. 11, p. 1312-1323

Publication date2016

Abstract

In pulmonary arterial hypertension (PAH), acute vasodilator response testing (AVT) is considered important to identify adult patients with favorable prognosis using calcium-channel blocker (CCB) therapy. However, in pediatric PAH, criteria used to identify acute responders and CCB use are insufficiently studied.

Keywords

Administration, Inhalation
Adolescent
Calcium Channel Blockers/therapeutic use
Cardiac Catheterization
Child
Child, Preschool
Dose-Response Relationship, Drug
Endothelium-Dependent Relaxing Factors/administration & dosage
Familial Primary Pulmonary Hypertension/drug therapy/physiopathology
Female
Follow-Up Studies
Humans
Infant
Male
Nitric Oxide/administration & dosage
Prognosis
Pulmonary Wedge Pressure/drug effects
Registries
Retrospective Studies
Vasodilation/drug effects
Vasodilator Agents/therapeutic use

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

L'hypertension pulmonaire (pédiatrie) (228)

Citation (ISO format)

DOUWES, Johannes M et al. Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry. In: Journal of the American College of Cardiology, 2016, vol. 67, n° 11, p. 1312–1323. doi: 10.1016/j.jacc.2016.01.015

Article (Published version)

OA OTHER

Identifiers

PID : unige:96718
DOI : 10.1016/j.jacc.2016.01.015
PMID : 26988953

Journal ISSN0735-1097

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136downloads

Creation14/09/2017 16:09:00

First validation14/09/2017 16:09:00

Update time15/03/2023 03:00:14

Status update15/03/2023 03:00:13

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Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry

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