UNIGE document Scientific Article
previous document  unige:96658  next document
add to browser collection

Prevalence and diversity of chlamydiales and other amoeba-resisting bacteria in domestic drinking water systems

Lienard, J
Croxatto, A
Lévi, Y
Loret, J-F
Greub, G
Published in New Microbes and New Infections. 2017, vol. 15, p. 107-116
Abstract A growing number of human infections incriminate environmental bacteria that have evolved virulent mechanisms to resist amoebae and use them as a replicative niche. These bacteria are designated amoeba-resisting bacteria (ARB). Despite the isolation of these ARB in various human clinical samples, the possible source of infection remains undetermined in most cases. However, it is known that the ARB Legionella pneumophila, for instance, causes a respiratory infection in susceptible hosts after inhalation of contaminated water aerosols from various sources. The Chlamydiales order contains many ARB, such as Parachlamydia acanthamoebae or Simkania negevensis, previously implicated in human respiratory infections with no identified contamination sources. We thus investigated whether domestic water systems are a potential source of transmission of these Chlamydiales to humans by using amoebal culture and molecular methods. Other important ARB such as mycobacteria and Legionella were also investigated, as were their possible amoebal hosts. This work reports for the first time a very high prevalence and diversity of Chlamydiales in drinking water, being detected in 35 (72.9%) of 48 investigated domestic water systems, with members of the Parachlamydiaceae family being dominantly detected. Furthermore, various Legionella and mycobacteria species were also recovered, some species of which are known to be causal agents of human infections.
PMID: 28070335
Full text
Article (Published version) (648 Kb) - public document Free access
Research groups Etiologie des pneumonies et marqueurs inflammatoires chez l'enfant fébrile (183)
Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
(ISO format)
LIENARD, J et al. Prevalence and diversity of chlamydiales and other amoeba-resisting bacteria in domestic drinking water systems. In: New microbes and new infections, 2017, vol. 15, p. 107-116. doi: 10.1016/j.nmni.2016.10.003 https://archive-ouverte.unige.ch/unige:96658

309 hits



Deposited on : 2017-09-13

Export document
Format :
Citation style :