MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties

Dietl, Sebastian; Schwinn, Stefanie; Dietl, Susanne; Riedel, Simone; Deinlein, Frank; Rutkowski, Stefan; Von Bueren, André; Krauss, Jürgen; Schweitzer, Tilmann; Vince, Giles H; Picard, Daniel; Eyrich, Matthias; Rosenwald, Andreas; Ramaswamy, Vijay; Taylor, Michael D; Remke, Marc; Monoranu, Camelia M; Beilhack, Andreas; Schlegel, Paul G; Wölfl, Matthias

doi:10.1186/s12885-016-2170-z

Scientific article

English

MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties

Published inBMC Cancer, vol. 16, 115

Publication date2016

Abstract

Medulloblastoma is the most common malignant brain tumor in children and can be divided in different molecular subgroups. Patients whose tumor is classified as a Group 3 tumor have a dismal prognosis. However only very few tumor models are available for this subgroup.

Keywords

Animals
Biomarkers, Tumor
Cell Line, Tumor
Female
Humans
Infant
Male
Medulloblastoma/pathology
Mice
Mice, SCID
Neoplasms, Experimental/pathology
Neoplastic Stem Cells
Xenograft Model Antitumor Assays

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

Research groups

Oncologie et hématologie pédiatriques (907)

Citation (ISO format)

DIETL, Sebastian et al. MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties. In: BMC Cancer, 2016, vol. 16, p. 115. doi: 10.1186/s12885-016-2170-z

Article (Published version)

CC0

Identifiers

PID : unige:96550
DOI : 10.1186/s12885-016-2170-z
PMID : 26883117

Journal ISSN1471-2407

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Update13/10/2025 19:49:26

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MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties

Medulloblastoma is the most common malignant brain tumor in children and can be divided in different molecular subgroups. Patients whose tumor is classified as a Group 3 tumor have a dismal prognosis. However only very few tumor models are available for this subgroup.

Technical informations