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Scientific article
English

Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma

Published inChild's Nervous System, vol. 32, no. 2, p. 281-290
Publication date2016
Abstract

The aim of this study was to investigate the epidermal growth factor receptor (EGFR) status in ependymoma specimens, as there is a need for new prognostic and druggable targets in this disease.

Keywords
  • Adolescent
  • Adult
  • Aged
  • Brain Neoplasms/genetics
  • Child
  • Child, Preschool
  • Ependymoma/genetics
  • Female
  • Gene Dosage/genetics
  • Humans
  • Immunohistochemistry
  • In Situ Hybridization, Fluorescence
  • Infratentorial Neoplasms/genetics
  • Male
  • Middle Aged
  • Mutation
  • Receptor, Epidermal Growth Factor/genetics
  • Spinal Cord Neoplasms/genetics
  • Supratentorial Neoplasms/genetics
  • Tissue Array Analysis
  • Young Adult
Citation (ISO format)
FRIEDRICH, Carsten et al. Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma. In: Child’s Nervous System, 2016, vol. 32, n° 2, p. 281–290. doi: 10.1007/s00381-015-2981-2
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Article (Published version)
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Identifiers
ISSN of the journal0256-7040
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