UNIGE document Scientific Article
previous document  unige:96077  next document
add to browser collection
Title

The biomarker-based diagnosis of Alzheimer's disease. 1-ethical and societal issues

Authors
Porteri, Corinna
Scerri, Charles
Carrillo, Maria C
Snyder, Heather M.
Martensson, Birgitta
Baker, Mark
show hidden authors show all authors [1 - 12]
Published in Neurobiology of Aging. 2017, vol. 52, p. 132-140
Abstract There is great interest in the use of biomarkers to assist in the timely identification of Alzheimer's disease (AD) in individuals with mild symptoms. However, the inclusion of AD biomarkers in clinical criteria poses socioethical challenges. The Geneva Task Force for the Roadmap of Alzheimer's Biomarkers was established to deliver a systematic strategic research agenda (aka roadmap) to promote efficient and effective validation of AD biomarkers and to foster their uptake in clinical practice. In this article, we summarize the workshop discussion of the Geneva Task Force "ethical and societal issues" working group, which comprised bioethicists, clinicians, health economists, and representatives of those affected by AD. The working group identified the following key issues that need to be included in the roadmap: improving access to services through timely diagnosis, the need for a diagnostic research protocol before moving to clinical routine, recruitment in diagnostic research protocols in the absence of effective therapy, respect for the autonomy of the individual with mild cognitive impairment in information and consent process and the right not to know biomarkers results, need for counseling programs, disclosure of the diagnosis in a structured environment and the involvement of family members, health policies including the individuals' views and the protection of their interests, and the economic costs for society.
Identifiers
PMID: 28317644
Full text
Article (Published version) (350 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research group Ethique biomédicale (783)
Citation
(ISO format)
PORTERI, Corinna et al. The biomarker-based diagnosis of Alzheimer's disease. 1-ethical and societal issues. In: Neurobiology of Aging, 2017, vol. 52, p. 132-140. https://archive-ouverte.unige.ch/unige:96077

20 hits

3 downloads

Update

Deposited on : 2017-08-08

Export document
Format :
Citation style :