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Title

Targeting the characteristics of multiple myeloma cancer stem cells with natural products

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Director
Defense Thèse de doctorat : Univ. Genève, 2017 - Sc. 5077 - 2017/06/02
Abstract This thesis describes the identification and the characterization of natural products that target multiple myeloma cancer stem cells. In this thesis, the effects of three natural products, bruceantin, withaferin A and withanolide D, on the proliferation, differentiation and resistance of multiple myeloma cancer stem cells, respectively, were examined. Results indicated that these natural products warrant further investigation in additional myeloma stem cell models and in mouse models.
Keywords MyelomaCancerStemCellsBruceantinWithaferin AWithanolide DProliferationDifferentiationResistance
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URN: urn:nbn:ch:unige-950783
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Thesis (4.9 MB) - private document Private access (until 2019-06-22)
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Research group Pharmacognosie
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ISSA, Mark Elia. Targeting the characteristics of multiple myeloma cancer stem cells with natural products. Université de Genève. Thèse, 2017. https://archive-ouverte.unige.ch/unige:95078

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Deposited on : 2017-06-26

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