en
Scientific article
Open access
English

The Structural Basis of Ligand Perception and Signal Activation by Receptor Kinases

Published inAnnual review of plant biology, vol. 68, no. 1, p. 109-137
Publication date2017
Abstract

Plants have evolved a family of unique membrane receptor kinases to orchestrate the growth and development of their cells, tissues, and organs. Receptor kinases also form the first line of defense of the plant immune system and allow plants to engage in symbiotic interactions. Here, we discuss recent advances in understanding, at the molecular level, how receptor kinases with lysin-motif or leucine-rich-repeat ectodomains have evolved to sense a broad spectrum of ligands. We summarize and compare the established receptor activation mechanisms for plant receptor kinases and dissect how ligand binding at the cell surface leads to activation of cytoplasmic signaling cascades. Our review highlights that one family of plant membrane receptors has diversified structurally to fulfill very different signaling tasks.

Research group
Citation (ISO format)
HOHMANN, Ulrich, LAU, Kelvin, HOTHORN, Michael. The Structural Basis of Ligand Perception and Signal Activation by Receptor Kinases. In: Annual review of plant biology, 2017, vol. 68, n° 1, p. 109–137. doi: 10.1146/annurev-arplant-042916-040957
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal1543-5008
542views
263downloads

Technical informations

Creation06/15/2017 12:20:00 PM
First validation06/15/2017 12:20:00 PM
Update time03/15/2023 1:46:51 AM
Status update03/15/2023 1:46:51 AM
Last indexation01/17/2024 12:09:48 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack