Smart environments interconnect indoor building environments, indoor wireless sensor and actuator networks, smartphones, and human together to provide smart infrastructure management and intelligent user experiences. To enable the "smart" operations, a complete set of hardware and software components are required. In this work, we present Smart Syndesi, a system for creating indoor location-aware smart building environments using wireless sensor and actuator networks (WSANs). Smart Syndesi includes an indoor tracking system, a WSAN for indoor environmental monitoring and activation automation, and a gateway interconnecting WSAN, tracking system with mobile users. The indoor positioning system tracks the real-time location of occupants with high accuracy, which works as a basis for indoor location-based sensor actuation automation. To show how the multiple software/hardware components are integrated, we implemented the system prototype and performed intensive experiments in indoor office environments to automate the indoor location-driven environmental sensor monitoring and activation process. The tracked indoor location of a user's smartphone triggers the retrieval of environmental measurements and activates the actuators automatically (i.e. turn on/off lights, switch on/off fans) based on the location and correlated environmental sensor information.