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Sudden cardiac death and sarcoidosis of the heart in a young patient

Jotterand, Morgane
Michaud, Katarzyna
Published in Cardiovascular Pathology. 2017, vol. 28, p. 18-20
Abstract Sarcoidosis is a granulomatous disease of unknown etiology affecting any organ, microscopically characterized by noncaseating granulomata. Cardiac involvement in sarcoidosis has been reported. It might be symptomatic or not and even revealed by sudden death. Heart conduction system is rarely investigated at autopsy, even in cases of sudden cardiac death. We present a case of a 32-year-old woman who died suddenly. The examination of the heart conduction system revealed a cardiac sarcoidosis that could explain the sudden death. The review of clinical data of the patient revealed some symptoms consistent/in agreement with this hypothesis. Cardiac sarcoidosis remains a diagnostic challenge and can be easily missed, clinically and pathologically. The retrospective analysis of clinical data and autopsy results of fatal and unusual cases might help to better understand sarcoidosis and its clinical presentations. Examination of the cardiac conduction system is crucial in selected cases of sudden cardiac death.
PMID: 28282543
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Research group Groupe Silke Grabherr (969)
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JOTTERAND, Morgane et al. Sudden cardiac death and sarcoidosis of the heart in a young patient. In: Cardiovascular Pathology, 2017, vol. 28, p. 18-20. doi: 10.1016/j.carpath.2017.01.003 https://archive-ouverte.unige.ch/unige:94220

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Deposited on : 2017-05-12

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