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Title

Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?

Authors
Lanthier, N
Published in Stem Cell Research and Therapy. 2017, vol. 8, no. 1, p. 88
Abstract Liver stem cell therapy (SCT) has been suggested as a promising means to improve liver regeneration in advanced liver disease. However, data from trials are heterogeneous, with no systematic histological evaluation. The aim of this study is to specifically analyze the effect of autologous SCT on liver regeneration and on gene expression changes.
Keywords AdultAgedAntigens, CD/genetics/metabolismAntigens, CD45/genetics/metabolismAntigens, Differentiation, Myelomonocytic/genetics/metabolismCarrier Proteins/genetics/metabolismCollagen Type I/genetics/metabolismFemaleHepatocyte Growth Factor/genetics/metabolismHumansLiver/metabolism/pathologyLiver Diseases, Alcoholic/therapyMacrophages/metabolismMaleMesenchymal Stem Cell Transplantation/adverse effectsMesenchymal Stromal Cells/cytology/metabolismMiddle AgedSerum Amyloid A Protein/genetics/metabolismTranscriptomeTransplantation, Autologous/adverse effects
Identifiers
PMID: 28420441
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Research group Métastases du foie (657)
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LANTHIER, N et al. Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?. In: Stem Cell Research & Therapy, 2017, vol. 8, n° 1, p. 88. https://archive-ouverte.unige.ch/unige:94214

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Deposited on : 2017-05-12

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