Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations

Premi, Enrico; Garibotto, Valentina; Gazzina, Stefano; Formenti, Anna; Archetti, Silvana; Gasparotti, Roberto; Padovani, Alessandro; Borroni, Barbara

doi:10.1159/000355428

Scientific article

English

Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations

ContributorsPremi, Enrico; Garibotto, Valentina

; Gazzina, Stefano; Formenti, Anna; Archetti, Silvana; Gasparotti, Roberto; Padovani, Alessandro; Borroni, Barbara

Published inDementia and geriatric cognitive disorders. Extra, vol. 4, no. 1, p. 95-102

Publication date2014

Abstract

Parkinsonism is often associated with symptoms of frontotemporal dementia (FTD), but its pathogenesis has been largely neglected. In genetic inherited FTD-related granulin (GRN) mutations, parkinsonism is an early sign, and it is more common than in sporadic disorders. Our aim was to study grey matter (GM) volume changes in subcortical and deep cortical regions in GRN-related FTD.

Affiliation

Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

Research group

Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)

Citation (ISO format)

PREMI, Enrico et al. Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations. In: Dementia and geriatric cognitive disorders. Extra, 2014, vol. 4, n° 1, p. 95–102. doi: 10.1159/000355428

Article (Published version)

Identifiers

PID : unige:94191
DOI : 10.1159/000355428
PMID : 24926307

ISSN of the journal1664-5464

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Subcortical and Deep Cortical Atrophy in Frontotemporal Dementia due to Granulin Mutations

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