Beyond cognitive reserve: behavioural reserve hypothesis in Frontotemporal Dementia

Premi, Enrico; Garibotto, Valentina; Gazzina, Stefano; Grassi, Mario; Cosseddu, Maura; Paghera, Barbara; Turla, Marinella; Padovani, Alessandro; Borroni, Barbara

doi:10.1016/j.bbr.2013.01.030

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Title		Beyond cognitive reserve: behavioural reserve hypothesis in Frontotemporal Dementia
Authors		Premi, Enrico Garibotto, Valentina Gazzina, Stefano Grassi, Mario Cosseddu, Maura Paghera, Barbara Turla, Marinella Padovani, Alessandro Borroni, Barbara show all authors [1 - 9]
Published in		Behavioural Brain Research. 2013, vol. 245, p. 58-62
Abstract		The brain reserve hypothesis posits that there are individual differences in the ability to cope with brain pathology, and that brain damage extent and clinical symptoms are not tightly linked. If cognitive reserve hypothesis has been demonstrated in Alzheimer Disease and Frontotemporal Dementia (FTD), no evidence of reserve mechanisms on behavioural disturbances has been corroborated yet. In FTD, distinct behavioural phenotypes may be identified.
Keywords		Aged — Behavior/physiology — Brain/diagnostic imaging — Brain Mapping — Caudate Nucleus/blood supply/diagnostic imaging — Cognitive Reserve/physiology — Cysteine/analogs & derivatives — Educational Status — Factor Analysis, Statistical — Female — Frontal Lobe/blood supply/diagnostic imaging — Frontotemporal Dementia/diagnostic imaging/psychology — Humans — Image Processing, Computer-Assisted — Male — Middle Aged — Neuropsychological Tests — Organotechnetium Compounds — Radiopharmaceuticals — Regression Analysis — Tomography, Emission-Computed, Single-Photon
Identifiers		DOI: 10.1016/j.bbr.2013.01.030 PMID: 23380679
Full text		Article (Published version) (416 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group		Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)
Citation (ISO format)		PREMI, Enrico et al. Beyond cognitive reserve: behavioural reserve hypothesis in Frontotemporal Dementia. In: Behavioural Brain Research, 2013, vol. 245, p. 58-62. doi: 10.1016/j.bbr.2013.01.030 https://archive-ouverte.unige.ch/unige:94188