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Beyond cognitive reserve: behavioural reserve hypothesis in Frontotemporal Dementia

Premi, Enrico
Gazzina, Stefano
Grassi, Mario
Cosseddu, Maura
Paghera, Barbara
Turla, Marinella
Padovani, Alessandro
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Published in Behavioural brain research. 2013, vol. 245, p. 58-62
Abstract The brain reserve hypothesis posits that there are individual differences in the ability to cope with brain pathology, and that brain damage extent and clinical symptoms are not tightly linked. If cognitive reserve hypothesis has been demonstrated in Alzheimer Disease and Frontotemporal Dementia (FTD), no evidence of reserve mechanisms on behavioural disturbances has been corroborated yet. In FTD, distinct behavioural phenotypes may be identified.
Keywords AgedBehavior/physiologyBrain/diagnostic imagingBrain MappingCaudate Nucleus/blood supply/diagnostic imagingCognitive Reserve/physiologyCysteine/analogs & derivativesEducational StatusFactor Analysis, StatisticalFemaleFrontal Lobe/blood supply/diagnostic imagingFrontotemporal Dementia/diagnostic imaging/psychologyHumansImage Processing, Computer-AssistedMaleMiddle AgedNeuropsychological TestsOrganotechnetium CompoundsRadiopharmaceuticalsRegression AnalysisTomography, Emission-Computed, Single-Photon
PMID: 23380679
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Research group Laboratoire de neuroimagerie et de traceurs moléculaires innovants (984)
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PREMI, Enrico et al. Beyond cognitive reserve: behavioural reserve hypothesis in Frontotemporal Dementia. In: Behavioural brain research, 2013, vol. 245, p. 58-62. doi: 10.1016/j.bbr.2013.01.030 https://archive-ouverte.unige.ch/unige:94188

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Deposited on : 2017-05-11

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