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Scientific article
English

In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease

Published inParkinsonism & related disorders, vol. 19, no. 1, p. 47-52
Publication date2013
Abstract

Reactive microgliosis, hallmark of neuroinflammation, may contribute to neuronal degeneration, as shown in several neurodegenerative diseases. We in vivo evaluated microglia activation in early dementia with Lewy bodies, still not reported, and compared with early Parkinson's disease, to assess possible differential pathological patterns.

Keywords
  • Aged
  • Aged, 80 and over
  • Brain/metabolism/pathology
  • Dementia/metabolism/pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Lewy Bodies/metabolism/pathology
  • Male
  • Microglia/metabolism/pathology
  • Neurodegenerative Diseases/metabolism/pathology
  • Neuroimaging/methods
  • Parkinson Disease/metabolism/pathology
  • Substantia Nigra/metabolism/pathology
Citation (ISO format)
IANNACCONE, S et al. In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson’s disease. In: Parkinsonism & related disorders, 2013, vol. 19, n° 1, p. 47–52. doi: 10.1016/j.parkreldis.2012.07.002
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Article (Published version)
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Identifiers
ISSN of the journal1353-8020
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