A significant effect of the killer cell immunoglobulin-like receptor ligand human leucocyte antigen-C on fibrosis progression in chronic C hepatitis with or without liver transplantation

Buhler, Stéphane; Giostra, Emiliano; Gbame, Corinne; De Rham, Casimir; Mullhaupt, Beat; Dufour, Jean-François Jacques; Majno, Pietro; Negro, Francesco; Bochud, Pierre-Yves; Villard, Jean

doi:10.1111/liv.13057

Scientific article

English

A significant effect of the killer cell immunoglobulin-like receptor ligand human leucocyte antigen-C on fibrosis progression in chronic C hepatitis with or without liver transplantation

ContributorsBuhler, Stéphane

; Giostra, Emiliano; Gbame, Corinne; De Rham, Casimir; Mullhaupt, Beat; Dufour, Jean-François Jacques; Majno, Pietro; Negro, Francesco; Bochud, Pierre-Yves; Villard, Jean

Published inLiver international, vol. 36, no. 9, p. 1331-1339

Publication date2016

Abstract

The interaction of killer cell immunoglobulin-like receptors with their human leucocyte antigen ligands drives the activation and inhibition of natural killer cells. Natural killer cells could be implicated in the development of liver fibrosis in chronic hepatitis C.

Keywords

HLA
KIR
chronic C hepatitis
fibrosis
liver transplantation

Affiliation entities

Research groups

Citation (ISO format)

BUHLER, Stéphane et al. A significant effect of the killer cell immunoglobulin-like receptor ligand human leucocyte antigen-C on fibrosis progression in chronic C hepatitis with or without liver transplantation. In: Liver international, 2016, vol. 36, n° 9, p. 1331–1339. doi: 10.1111/liv.13057

Article (Published version)

Identifiers

PID : unige:93790
DOI : 10.1111/liv.13057
PMID : 26717049

Journal ISSN1478-3223

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A significant effect of the killer cell immunoglobulin-like receptor ligand human leucocyte antigen-C on fibrosis progression in chronic C hepatitis with or without liver transplantation

The interaction of killer cell immunoglobulin-like receptors with their human leucocyte antigen ligands drives the activation and inhibition of natural killer cells. Natural killer cells could be implicated in the development of liver fibrosis in chronic hepatitis C.

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