Human microRNA responses predict cytomegalovirus replication following solid organ transplantation

Sang, Hoon Han; Kumar, Dheeraj; Ferreira, V H; Egli, A; Hirsch, H H; Weisser, Markus; Garzoni, Christian; Van Delden, Christian; Bochud, Pierre-Yves; Manuel, O; Meylan, Pascal; Boggian, K; Husain, S; Mueller, Neitah; Humar, A

doi:10.1093/infdis/jiw596

Scientific article

English

Human microRNA responses predict cytomegalovirus replication following solid organ transplantation

ContributorsSang, Hoon Han; Kumar, Dheeraj; Ferreira, V H; Egli, A; Hirsch, H H; Weisser, Markus; Garzoni, Christian; Van Delden, Christian; Bochud, Pierre-Yves; Manuel, O; Meylan, Pascal; Boggian, K; Husain, S; Mueller, Neitah; Humar, A

Published inThe Journal of infectious diseases, vol. 215, no. 4, p. 537-546

Publication date2017

Abstract

Homo sapiens mature microRNA-200b-3p and -200c-3p are predicted to bind to 3' UTR of mRNA encoding human cytomegalovirus (HCMV) immediate early protein 2 (IE2). We hypothesized that expression of these microRNAs pre-transplant could predict HCMV replication after solid organ transplantation (SOT).

Keywords

cytomegalovirus
immediate early protein
microRNA
solid organ transplant

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Citation (ISO format)

SANG, Hoon Han et al. Human microRNA responses predict cytomegalovirus replication following solid organ transplantation. In: The Journal of infectious diseases, 2017, vol. 215, n° 4, p. 537–546. doi: 10.1093/infdis/jiw596

Article (Accepted version)

Identifiers

PID : unige:93785
DOI : 10.1093/infdis/jiw596
PMID : 28003351

Journal ISSN0022-1899

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Human microRNA responses predict cytomegalovirus replication following solid organ transplantation

Homo sapiens mature microRNA-200b-3p and -200c-3p are predicted to bind to 3' UTR of mRNA encoding human cytomegalovirus (HCMV) immediate early protein 2 (IE2). We hypothesized that expression of these microRNAs pre-transplant could predict HCMV replication after solid organ transplantation (SOT).

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