Article (Author postprint) (42 Kb) - Limited access to UNIGE
Donor-specific antibodies C1q-binding: improvement in kidney graft management?
|Published in||Transplant International. 2017, vol. 30, no. 4, p. 344-346|
|Abstract||The diagnosis of acute antibody mediated rejection (ABMR) after kidney transplantation is based on three parameters: 1) decreased renal function, 2) histopathological signs of rejection, 3) presence of Donor Specific Antibody (DSA) . Patient survival, as well as graft survival have improved since 5 to 10 years , thanks to several factors, including better management of patients, better immunosuppressive regimens, detection and avoidance of DSA. Although anti-HLA antibodies follow-up have improved ABMR management, its treatment remains challenging, and outcome may be worsened because of a delay in the diagnosis. This article is protected by copyright. All rights reserved.|
Faculté de médecine / Section de médecine clinique / Département de médecine interne des spécialités
|Research group||Transplantation et hépatologie (905)|
|FERRARI-LACRAZ, Sylvie. Donor-specific antibodies C1q-binding: improvement in kidney graft management?. In: Transplant International, 2017, vol. 30, n° 4, p. 344-346. https://archive-ouverte.unige.ch/unige:93772|