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Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons |
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Published in | Xenotransplantation. 2017, vol. 24, no. 3, e12297 | |
Abstract | There is no standard therapy for acute liver failure. Hepatocyte transplantation has been proposed for temporary liver function support, while the injured liver regenerates or while waiting for transplantation. We have previously shown such efficacy for microencapsulated porcine hepatocytes in mice with fulminant liver failure. We aimed to establish a large animal model for fulminant liver failure to assess the efficacy of microencapsulated porcine hepatocytes in temporary liver function support. | |
Keywords | cell microencapsulation — fulminant liver failure — hepatocyte transplantation — non-human primate — porcine hepatocytes | |
Identifiers | DOI: 10.1111/xen.12297 PMID: 28261903 | |
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Research groups | Chirurgie viscérale (104) Chirurgie viscérale (HUG) Transplantation et hépatologie (905) | |
Citation (ISO format) | MACHAIDZE, Zurab et al. Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons. In: Xenotransplantation, 2017, vol. 24, n° 3, p. e12297. doi: 10.1111/xen.12297 https://archive-ouverte.unige.ch/unige:93756 |