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Title

Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons

Authors
Machaidze, Zurab
Yeh, Heidi
Wei, Lingling
Schuetz, Christian
Carvello, Michele
Smith, Rex N
Schuurman, Henk-Jan
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Published in Xenotransplantation. 2017
Abstract There is no standard therapy for acute liver failure. Hepatocyte transplantation has been proposed for temporary liver function support, while the injured liver regenerates or while waiting for transplantation. We have previously shown such efficacy for microencapsulated porcine hepatocytes in mice with fulminant liver failure. We aimed to establish a large animal model for fulminant liver failure to assess the efficacy of microencapsulated porcine hepatocytes in temporary liver function support.
Keywords cell microencapsulationfulminant liver failurehepatocyte transplantationnon-human primateporcine hepatocytes
Identifiers
PMID: 28261903
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Article (Published version) (2.1 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Research groups Chirurgie viscérale (104)
Transplantation et hépatologie (905)
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(ISO format)
MACHAIDZE, Zurab et al. Testing of microencapsulated porcine hepatocytes in a new model of fulminant liver failure in baboons. In: Xenotransplantation, 2017. https://archive-ouverte.unige.ch/unige:93756

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Deposited on : 2017-04-21

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