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Fibrous Dysplasia Mimicking Malignancy on 68Ga-DOTATATE PET/CT.

Papadakis, Georgios Z
Millo, Corina
Karantanas, Apostolos H
Bagci, Ulas
Patronas, Nicholas J
Published in Clinical Nuclear Medicine. 2017, vol. 42, no. 3, p. 209-210
Abstract Fibrous dysplasia of the bone is a developmental benign skeletal disorder characterized by replacement of normal bone and normal bone marrow with abnormal fibro-osseous tissue. We report on a case of a biopsy-proven fibrous dysplasia lesion in the left temporal bone, with intensely increased activity (SUVmax, 56.7) on Ga-DOTATATE PET/CT. The presented data indicate cell surface overexpression of somatostatin receptors by fibrous dysplastic cells and highlight the need of cautious management of Ga-DOTATATE-avid bone lesions, which could mimic malignancy especially in patients with history of neuroendocrine tumors.
PMID: 28072620
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PAPADAKIS, Georgios Z et al. Fibrous Dysplasia Mimicking Malignancy on 68Ga-DOTATATE PET/CT. In: Clinical Nuclear Medicine, 2017, vol. 42, n° 3, p. 209-210. https://archive-ouverte.unige.ch/unige:93678

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Deposited on : 2017-04-21

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