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Chronic hemicorporal prurigo related to a posttraumatic Brown-Séquard syndrome

Publié dansDermatology, vol. 217, no. 1, p. 45-47
Date de publication2008
Résumé

Focal pruritus may have a neurological cause. According to the underlying mechanism, two categories of central itch have been distinguished, neuropathic and neurogenic pruritus. We here describe a patient with Brown-Séquard syndrome related to unilateral damage of the spinal cord. The patient progressively developed neuropathic pruritus with chronic prurigo lesions showing strictly hemicorporal distribution. The patient was given pregabalin, an analogue of the neurotransmitter gamma-aminobutyric acid,with significant improvement. Our observation of chronic prurigo with hemicorporal involvement is unique. It underscores the importance of a detailed neurological examination in case of persistent localized itch and further supports the idea that chronic prurigo reflects a neurological problem in a subset of affected patients. Antiepileptic drugs should be considered not only for neuropathic pain, but also for neuropathic itch.

Mots-clés
  • Adult
  • Anticonvulsants/therapeutic use
  • Antipruritics/therapeutic use
  • Brown-Sequard Syndrome/complications
  • Humans
  • Male
  • Neurologic Examination
  • Prurigo/drug therapy/etiology/pathology
  • Pruritus/drug therapy/etiology
  • Skin/innervation/pathology
  • Spinal Cord Injuries/complications
  • Gamma-Aminobutyric Acid/analogs & derivatives/therapeutic use
Citation (format ISO)
THIELEN, A M., VOKATCH, N., BORRADORI, Luca. Chronic hemicorporal prurigo related to a posttraumatic Brown-Séquard syndrome. In: Dermatology, 2008, vol. 217, n° 1, p. 45–47. doi: 10.1159/000121500
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Article (Accepted version)
accessLevelRestricted
Identifiants
ISSN du journal1018-8665
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Informations techniques

Création26/02/2009 11:41:00
Première validation26/02/2009 11:41:00
Heure de mise à jour14/03/2023 15:01:07
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