Enoxaparin Attenuates Mouse Colon Cancer Liver Metastases by Inhibiting Heparanase and Interferon-γ-inducible Chemokines

Djaafar, Souad; Dunand-Sauthier, Isabelle; Gonelle-Gispert, Carmen; Lacotte, Stéphanie; De Agostini, Ariane; Petro, ma; Rubbia-Brandt, Laura; Morel, Philippe; Toso, Christian; Mentha, Gilles

Scientific article

English

Enoxaparin Attenuates Mouse Colon Cancer Liver Metastases by Inhibiting Heparanase and Interferon-γ-inducible Chemokines

ContributorsDjaafar, Souad; Dunand-Sauthier, Isabelle; Gonelle-Gispert, Carmen; Lacotte, Stéphanie

; De Agostini, Ariane; Petro, ma; Rubbia-Brandt, Laura; Morel, Philippe; Toso, Christian

; Mentha, Gilles

Published inAnticancer research, vol. 36, no. 8, p. 4019-4032

Publication date2016

Abstract

Low-molecular-weight heparin (LMWH) has been suggested to reduce the risk of cancer progression in both preclinical and clinical studies but the underlying mechanisms remain poorly explored. The aim of the study was to investigate the anti-metastatic role of enoxaparin, a clinically-used LMWH, in a murine model of colon cancer and to explore its underlying mechanisms.

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Citation (ISO format)

DJAAFAR, Souad et al. Enoxaparin Attenuates Mouse Colon Cancer Liver Metastases by Inhibiting Heparanase and Interferon-γ-inducible Chemokines. In: Anticancer research, 2016, vol. 36, n° 8, p. 4019–4032.

Article (Submitted version)

Identifiers

PID : unige:93347
PMID : 27466508

Journal ISSN0250-7005

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Enoxaparin Attenuates Mouse Colon Cancer Liver Metastases by Inhibiting Heparanase and Interferon-γ-inducible Chemokines

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