Management of patients with colorectal liver metastasis in eleven questions and answers

Andres, Axel; Majno, Pietro; Terraz, Sylvain; Morel, Philippe; Roth, Arnaud; Rubbia-Brandt, Laura; Schiffer, Eduardo; Ris, Frédéric; Toso, Christian

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Title		Management of patients with colorectal liver metastasis in eleven questions and answers
Authors		Andres, Axel Majno, Pietro Terraz, Sylvain Morel, Philippe Roth, Arnaud Rubbia-Brandt, Laura Schiffer, Eduardo Ris, Frédéric Toso, Christian show all authors [1 - 9]
Published in		Expert Review of Anticancer Therapy. 2016, vol. 16, no. 12, p. 1277-1290
Abstract		Colorectal liver metastasis (CRLM) is the most frequent indication for liver resection in many centers. Recent improvements in oncology, surgery, interventional radiology, pathology and anesthesiology allow curative treatment in a larger proportion of patients with CRLM. Areas covered: We illustrate the various aspects of the management of CRLM through 11 questions that summarize the topic, from the current obtained survival to future perspectives such as transplantation. The limits of a curative treatment are also presented from different angles, such as the benefits of pathology, the surgical options for extreme resections, the available chemotherapies and their efficacy, or the non-surgical ablative treatments. Expert commentary: Given the increasing therapeutic possibilities, we strengthen the importance to analyze the situation of each patient with CRLM in a dedicated multidisciplinary team, in order to offer the best individualized treatment combination.
Keywords		Colorectal liver metastases — Liver locoregional treatment — Liver surgery — Liver transplantation — Liver cancer
Identifiers		DOI: 10.1080/14737140.2016.1249855 PMID: 27744725
Full text		Article (Published version) (1.6 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de chirurgie Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie et soins intensifs Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Chirurgie viscérale (104) Métastases du foie (657) Groupe Roth Arnaud (oncologie) (285) Transplantation et hépatologie (905) Imagerie per-opératoire multi-modalité en radiologie interventionnelle (949)
Citation (ISO format)		ANDRES, Axel et al. Management of patients with colorectal liver metastasis in eleven questions and answers. In: Expert Review of Anticancer Therapy, 2016, vol. 16, n° 12, p. 1277-1290. https://archive-ouverte.unige.ch/unige:93330