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Title

Nosocomial infections in Swiss university hospitals: a multi-centre survey and review of the published experience. Swiss-Noso Network
Authors
Harbarth, Stéphan Juergen
Ruef, C.
Francioli, P.
Widmer, Ariane
Pittet, Didier
Published in Schweizerische medizinische Wochenschrift. 1999, vol. 129, no. 42, p. 1521-1528
Abstract A one-week period-prevalence survey, aimed at assessing the scale of nosocomial infections, was conducted in May 1996 in medical, surgical, and intensive care wards of 4 Swiss university hospitals. Standard definitions by the Centres for Disease Control and Prevention were used except that asymptomatic bacteriuria was not classified as a nosocomial infection. A total of 176 nosocomial infections were found among 156 of the 1349 surveyed patients (prevalence 11.6%; interhospital range 9.8-13.5%). Surgical site infections were most prevalent (30% of all nosocomial infections), followed by urinary tract (22%), lower respiratory tract (15%), and bloodstream infections (13%). The most frequently isolated microorganisms were Enterobacteriaceae (n = 44; 28%), S. aureus (n = 20; 13%), Pseudomonas spp (n = 17; 11%), and Candida spp (n = 16; 10%). One third of all episodes of nosocomial infections were not microbiologically documented. The overall prevalence of nosocomial infections in surgical patients (n = 562) was 16.2% compared to 8.6% for non-surgical patients (prevalence ratio, 1.9; 95% confidence interval [CI95], 1.4-2.5). In one centre, the in-hospital mortality of patients with nosocomial infections was 9.2% (10/109) compared to 3.9% (25/637) for patients without nosocomial infections (odds ratio, 2.47; CI95, 1.15-5.31). Infection rates were similar to those reported by two Swiss pilot studies from the early 1980s. This study offers a reliable measure of the prevalence of nosocomial infections in selected wards at 4 Swiss university hospitals and confirms the importance of nosocomial infections as a heavy burden on health services at the end of this century.
Keywords Blood-Borne Pathogens — Candidiasis/epidemiology — Cross Infection/classification/ epidemiology/mortality — Enterobacteriaceae Infections/epidemiology — Hospital Units/statistics & numerical data — Hospitals, University/ statistics & numerical data — Humans — Prevalence — Respiratory Tract Infections/epidemiology — Risk Factors — Staphylococcal Infections/epidemiology — Switzerland/epidemiology — Urinary Tract Infections/epidemiology
Identifiers
PMID: 10568234
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Structures
Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement
Research groups Epidémiologie et contrôle de la résistance aux antibiotiques (866)
Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière (330)
Citation
(ISO format) 		HARBARTH, Stéphan Juergen et al. Nosocomial infections in Swiss university hospitals: a multi-centre survey and review of the published experience. Swiss-Noso Network. In: Schweizerische medizinische Wochenschrift, 1999, vol. 129, n° 42, p. 1521-1528. https://archive-ouverte.unige.ch/unige:9333

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Deposited on : 2010-07-12

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