Visual memory profile in 22q11.2 microdeletion syndrome: are there differences in performance and neurobiological substrates between tasks linked to ventral and dorsal visual brain structures? A cross-sectional and longitudinal study

Bostelmann, Mathilde; Schneider, Maude; Padula, Maria; Maeder, Johanna; Schaer, Marie; Scariati Jaussi, Elisa; Debbané, Martin; Glaser, Bronwyn; Menghetti, Sarah; Eliez, Stéphan

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Title		Visual memory profile in 22q11.2 microdeletion syndrome: are there differences in performance and neurobiological substrates between tasks linked to ventral and dorsal visual brain structures? A cross-sectional and longitudinal study
Authors		Bostelmann, Mathilde Schneider, Maude Padula, Maria Maeder, Johanna Schaer, Marie Scariati Jaussi, Elisa Debbané, Martin Glaser, Bronwyn Menghetti, Sarah Eliez, Stéphan show all authors [1 - 10]
Published in		Journal of Neurodevelopmental Disorders. 2016, vol. 8, p. 41
Abstract		Children affected by the 22q11.2 deletion syndrome (22q11.2DS) have a specific neuropsychological profile with strengths and weaknesses in several cognitive domains. Specifically, previous evidence has shown that patients with 22q11.2DS have more difficulties memorizing faces and visual-object characteristics of stimuli. In contrast, they have better performance in visuo-spatial memory tasks. The first focus of this study was to replicate these results in a larger sample of patients affected with 22q11.2DS and using a range of memory tasks. Moreover, we analyzed if the deficits were related to brain morphology in the structures typically underlying these abilities (ventral and dorsal visual streams). Finally, since the longitudinal development of visual memory is not clearly characterized in 22q11.2DS, we investigated its evolution from childhood to adolescence.
Identifiers		DOI: 10.1186/s11689-016-9174-5 PMID: 27843501
Full text		Article (Published version) (678 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de psychologie et des sciences de l'éducation / Section de psychologie
Research groups		Laboratoire d'imagerie et de psychopathologie développementale (693) Unité de psychologie clinique de l'adolescence (UPCA)
Citation (ISO format)		BOSTELMANN, Mathilde et al. Visual memory profile in 22q11.2 microdeletion syndrome: are there differences in performance and neurobiological substrates between tasks linked to ventral and dorsal visual brain structures? A cross-sectional and longitudinal study. In: Journal of Neurodevelopmental Disorders, 2016, vol. 8, p. 41. https://archive-ouverte.unige.ch/unige:93284