Scientific article

Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use

Published inJournal of cataract and refractive surgery, vol. 35, no. 4, p. 788-791
Publication date2009

A 32-year-old man with keratoconus developed corneal melting 5 days after riboflavin/ultraviolet-A corneal collagen crosslinking (CXL). Corneal scraping was positive for Acanthamoeba. The patient was unaware that he was wearing a bandage contact lens and repeatedly rinsed his face and eyelids with tap water. Because of corneal perforation, a large therapeutic keratoplasty à chaud was performed. Although CXL is considered a safe procedure, this case emphasizes the potential risks. We discuss the potential effects of deepithelialization, contact lens placement, instillation of topical nonsteroidal antiinflammatory drugs and anesthetic agents, and the possible role of apoptosis when performing CXL treatment for keratoconus.

  • Acanthamoeba Keratitis/etiology/surgery
  • Adult
  • Bandages
  • Collagen/metabolism
  • Contact Lenses
  • Cornea/metabolism/parasitology
  • Humans
  • Keratoconus/drug therapy/metabolism
  • Keratoplasty, Penetrating
  • Male
  • Photochemotherapy
  • Photosensitizing Agents/therapeutic use
  • Postoperative Complications
  • Riboflavin/therapeutic use
  • Rupture, Spontaneous
  • Ultraviolet Rays
Affiliation Not a UNIGE publication
Citation (ISO format)
RAMA, Paolo et al. Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use. In: Journal of cataract and refractive surgery, 2009, vol. 35, n° 4, p. 788–791. doi: 10.1016/j.jcrs.2008.09.035
Main files (1)
Article (Published version)
ISSN of the journal0886-3350

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