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Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus

Ionescu, Catalina
Corbu, Catalina Gabriela
Tanase, Cristiana
Nicula, Cristina
Dascalescu, Dana
Cristea, Miruna
Voinea, Liliana-Mary
Published in Disease Markers. 2016, vol. 2016, p. 1243819
Abstract Keratoconus is a degenerative disorder with progressive stromal thinning and transformation of the normal corneal architecture towards ectasia that results in decreased vision due to irregular astigmatism and irreversible tissue scarring. The pathogenesis of keratoconus still remains unclear. Hypotheses that this condition has an inflammatory etiopathogenetic component apart from the genetic and environmental factors are beginning to escalate in the research domain. This paper covers the most relevant and recent published papers regarding the biomarkers of inflammation, their signaling pathway, and the potentially new therapeutic options in keratoconus.
PMID: 27563164
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Article (Published version) (1.3 MB) - public document Free access
Research group Ophtalmologie expérimentale (925)
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IONESCU, Catalina et al. Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus. In: Disease Markers, 2016, vol. 2016, p. 1243819. https://archive-ouverte.unige.ch/unige:93155

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Deposited on : 2017-04-05

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