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Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus

Contributors

Ionescu, Catalina; Corbu, Catalina Gabriela; Tanase, Cristiana; Jonescu-Cuypers, Christian Paul; Nicula, Cristina; Dascalescu, Dana; Cristea, Miruna; Voinea, Liliana-Mary

Published in

Disease markers, vol. 2016, 1243819

Publication date

2016

Abstract

Keratoconus is a degenerative disorder with progressive stromal thinning and transformation of the normal corneal architecture towards ectasia that results in decreased vision due to irregular astigmatism and irreversible tissue scarring. The pathogenesis of keratoconus still remains unclear. Hypotheses that this condition has an inflammatory etiopathogenetic component apart from the genetic and environmental factors are beginning to escalate in the research domain. This paper covers the most relevant and recent published papers regarding the biomarkers of inflammation, their signaling pathway, and the potentially new therapeutic options in keratoconus.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

IONESCU, Catalina et al. Inflammatory Biomarkers Profile as Microenvironmental Expression in Keratoconus. In: Disease markers, 2016, vol. 2016, p. 1243819. doi: 10.1155/2016/1243819

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

0278-0240
506views
525downloads

Technical informations

Creation

30/11/2016 09:25:00

First validation

30/11/2016 09:25:00

Update

15/03/2023 01:32:11

Status update

15/03/2023 01:32:10

Last indexation

31/10/2024 06:37:41
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