Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers
Published inJournal of medicinal chemistry, vol. 55, no. 22, p. 9693-9707
Publication date2012
Abstract
Keywords
- Animals
- Dioxanes/pharmacology
- Drug Design
- Humans
- Iodine Radioisotopes
- Ligands
- Mice
- Molecular Probes
- Piperidines/pharmacology
- Radioligand Assay
- Radiopharmaceuticals
- Receptors, Serotonin, 5-HT4/chemistry/metabolism
- Serotonin 5-HT4 Receptor Antagonists/chemical synthesis/pharmacology
- Structure-Activity Relationship
- Tomography, Emission-Computed, Single-Photon
Affiliation Not a UNIGE publication
Research group
Citation (ISO format)
DUBOST, Emmanuelle et al. Synthesis and structure-affinity relationships of selective high-affinity 5-HT(4) receptor antagonists: application to the design of new potential single photon emission computed tomography tracers. In: Journal of medicinal chemistry, 2012, vol. 55, n° 22, p. 9693–9707. doi: 10.1021/jm300943r
Identifiers
- PID : unige:92657
- DOI : 10.1021/jm300943r
- PMID : 23102207
ISSN of the journal0022-2623