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Title

Dynamic Volume Assessment of Hepatocellular Carcinoma in Rat Livers Using a Clinical 3T MRI and Novel Segmentation
Authors
Orci, Lorenzo
Oldani, Graziano
Lacotte, Stéphanie
Slits, Florence
Friedli, Iris
Wirth, Wolfgang
Toso, Christian
Vallée, Jean-Paul
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Published in Journal of Investigative Surgery. 2017, p. 1-10
Abstract In vivo liver cancer research commonly uses rodent models. One of the limitations of such models is the lack of accurate and reproducible endpoints for a dynamic assessment of growing tumor nodules. The aim of this study was to validate a noninvasive, true volume segmentation method using two rat hepatocellular carcinoma (HCC) models, correlating magnetic resonance imaging (MRI) with histological volume measurement, and with blood levels of α-fetoprotein.
Identifiers
PMID: 28107094
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Article (Published version) (759 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Faculté de médecine / Section de médecine clinique / Département de chirurgie
Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups Transplantation et hépatologie (905)
Imagerie cardiaque fonctionnelle (541)
Citation
(ISO format) 		ORCI, Lorenzo et al. Dynamic Volume Assessment of Hepatocellular Carcinoma in Rat Livers Using a Clinical 3T MRI and Novel Segmentation. In: Journal of Investigative Surgery, 2017, p. 1-10. doi: 10.1080/08941939.2016.1276987 https://archive-ouverte.unige.ch/unige:92435

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Deposited on : 2017-03-08

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