Master
English

Dissecting and manipulating Htr3a-expressing cortical interneuron diversity

Master program titleMaîtrise universitaire en neurosciences
Defense date2017
Abstract

Cortical GABAergic interneurons constitute a highly diverse population in terms of embryonic origin, molecular identity, morphological and connectivity features, electrophysiological properties and laminar distribution. This large cellular diversity makes it difficult to study the specific function of inhibitory interneuronal subtypes in cortical microcircuits. Approximately 30% of cortical GABAergic interneurons are classified based on the expression of a specific serotoninergic receptor, the ionotropic serotonin receptor 5HT3a (Htr3a) and are often studied using the Htr3a-GFP mouse line. This population of Htr3a-expressing interneurons mainly arises from the embryonic caudal ganglionic eminence (CGE) and the study of its large diversity is a main focus of our laboratory...

Citation (ISO format)
GOMEZ TEIJEIRO, Lucia. Dissecting and manipulating Htr3a-expressing cortical interneuron diversity. Master, 2017.
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Master thesis
accessLevelPrivate
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  • PID : unige:92230
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Creation01/03/2017 10:41:00
First validation01/03/2017 10:41:00
Update15/03/2023 01:25:02
Status update15/03/2023 01:25:01
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