The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene

Berry, G. T.; Mallee, J. J.; Blouin, Jean-Louis; Antonarakis, Stylianos

doi:10.1159/000134311

Scientific article

English

The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene

ContributorsBerry, G. T.; Mallee, J. J.; Blouin, Jean-Louis; Antonarakis, Stylianos

Published inCytogenetics and cell genetics, vol. 73, no. 1-2, p. 77-78

Publication date1996

Abstract

The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3) was recently cloned and localized to the region of 21q22. Fine mapping of this gene was accomplished by identifying YAC clones that contain SLC5A3 and utilizing known STS markers for 21q22.1 and 21q22.2 sub-bands that map to the positive YAC clones. Two bacteriophage P1 clones containing the SLC5A3 gene gave a positive PCR product when screened with the 21q22.1 marker VN02, an expressed sequence tag (EST00541). Through DNA sequence analysis, it was determined that this STS marker if part of the 3' untranslated region of the SLC5A3 gene.

Keywords

Bacteriophages/genetics
Base Sequence
Carrier Proteins/ genetics
Chromosomes, Human, Pair 21/ genetics
DNA Primers
DNA, Complementary/genetics
Gene Expression
Genes
Genetic Markers
Heat-Shock Proteins/ genetics
Humans
Membrane Proteins
Molecular Sequence Data
Polymerase Chain Reaction
Symporters

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement

Citation (ISO format)

BERRY, G. T. et al. The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3′ sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene. In: Cytogenetics and cell genetics, 1996, vol. 73, n° 1-2, p. 77–78. doi: 10.1159/000134311

Identifiers

PID : unige:9142
DOI : 10.1159/000134311
PMID : 8646889

Additional URL for this publicationhttp://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=134311&Ausgabe=236117&ProduktNr=224037

Journal ISSN0301-0171

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The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene

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