en
Scientific article
English

Human chromosome 21: genome mapping and exploration, circa 1993

Published inTrends in genetics, vol. 9, no. 4, p. 142-148
Publication date1993
Abstract

Chromosome 21 is the smallest human chromosome, but one of considerable medical importance. A comprehensive physical map of overlapping YACs, a dense linkage map and an almost complete long-range restriction map have been produced much earlier than expected. These mapping accomplishments will greatly facilitate the exploration of chromosome 21, helping to characterize both genes and their impact in health and disease.

Keywords
  • Chromosome Aberrations/ genetics
  • Chromosome Disorders
  • Chromosome Mapping
  • Chromosomes, Human, Pair 21
  • Down Syndrome/genetics
  • Female
  • Humans
  • Linkage (Genetics)
  • Male
Citation (ISO format)
ANTONARAKIS, Stylianos. Human chromosome 21: genome mapping and exploration, circa 1993. In: Trends in genetics, 1993, vol. 9, n° 4, p. 142–148. doi: 10.1016/0168-9525(93)90210-9
Identifiers
ISSN of the journal0168-9525
548views
0downloads

Technical informations

Creation07/12/2010 2:35:54 PM
First validation07/12/2010 2:35:54 PM
Update time03/14/2023 3:53:30 PM
Status update03/14/2023 3:53:30 PM
Last indexation01/15/2024 8:46:45 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack