UNIGE document Scientific Article
previous document  unige:91081  next document
add to browser collection

Human calf microvascular compliance measured by near-infrared spectroscopy

Quaresima, V
Ferrari, M
Published in Journal of applied physiology. 2000, vol. 88, no. 2, p. 369-372
Abstract The purpose of this study is to develop a new method for the measurement in humans of the compliance of the microvascular superficial venous system of the lower limb by near-infrared spectroscopy (NIRS). This method is complementary to strain-gauge plethysmography, which does not allow compliance between deep and superficial venous or between venous and arterial compartments to be distinguished. In practice, hydrostatic pressure (P) changes were induced in a calf region of interest by head-up tilt of the subject from alpha = -10 to 75 degrees. For P < or = 24 mmHg, the measured compliance [0.086 +/- 0.005 (SD) ml. l(-1). mmHg(-1)] based on NIRS data of total, deoxygenated, and oxygenated hemoglobin, reflects essentially that of the superficial venous system. For P > or = 24 mmHg, no distinction can be made between arterial and venous volumes changes. However, by following the changes in oxy- and deoxyhemoglobin in the P range -16 to 100 mmHg, it appears to be possible to assess the characteristics of the vasomotor response of the arteriolar system.
Keywords AdultBlood Pressure/physiologyBlood Vessels/physiologyComplianceFemaleHemoglobins/metabolismHumansLeg/blood supplyMaleMiddle AgedMuscle, Skeletal/blood supplyOxyhemoglobins/metabolismPosture/physiologySpectroscopy, Near-Infrared/methodsSupine PositionTilt-Table TestVasomotor System/physiology
PMID: 10658000
Full text
Article (Published version) (73 Kb) - document accessible for UNIGE members only Limited access to UNIGE
Research group Groupe Binzoni Tiziano (radiologie) (234)
(ISO format)
BINZONI, Tiziano et al. Human calf microvascular compliance measured by near-infrared spectroscopy. In: Journal of applied physiology, 2000, vol. 88, n° 2, p. 369-372. https://archive-ouverte.unige.ch/unige:91081

253 hits

0 download


Deposited on : 2017-01-13

Export document
Format :
Citation style :