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Human calf microvascular compliance measured by near-infrared spectroscopy |
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Published in | Journal of applied physiology. 2000, vol. 88, no. 2, p. 369-372 | |
Abstract | The purpose of this study is to develop a new method for the measurement in humans of the compliance of the microvascular superficial venous system of the lower limb by near-infrared spectroscopy (NIRS). This method is complementary to strain-gauge plethysmography, which does not allow compliance between deep and superficial venous or between venous and arterial compartments to be distinguished. In practice, hydrostatic pressure (P) changes were induced in a calf region of interest by head-up tilt of the subject from alpha = -10 to 75 degrees. For P < or = 24 mmHg, the measured compliance [0.086 +/- 0.005 (SD) ml. l(-1). mmHg(-1)] based on NIRS data of total, deoxygenated, and oxygenated hemoglobin, reflects essentially that of the superficial venous system. For P > or = 24 mmHg, no distinction can be made between arterial and venous volumes changes. However, by following the changes in oxy- and deoxyhemoglobin in the P range -16 to 100 mmHg, it appears to be possible to assess the characteristics of the vasomotor response of the arteriolar system. | |
Keywords | Adult — Blood Pressure/physiology — Blood Vessels/physiology — Compliance — Female — Hemoglobins/metabolism — Humans — Leg/blood supply — Male — Middle Aged — Muscle, Skeletal/blood supply — Oxyhemoglobins/metabolism — Posture/physiology — Spectroscopy, Near-Infrared/methods — Supine Position — Tilt-Table Test — Vasomotor System/physiology | |
Identifiers | PMID: 10658000 | |
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Research group | Groupe Binzoni Tiziano (radiologie) (234) | |
Citation (ISO format) | BINZONI, Tiziano et al. Human calf microvascular compliance measured by near-infrared spectroscopy. In: Journal of applied physiology, 2000, vol. 88, n° 2, p. 369-372. https://archive-ouverte.unige.ch/unige:91081 |