Human tibia bone marrow blood perfusion by non-invasive near infrared spectroscopy: a new tool for studies on microgravity
|Published in||Journal of Gravitational Physiology. 2002, vol. 9, no. 1, p. P183-P184|
|Abstract||Human tibia bone marrow (BM) and tibialis anterior muscle (TA) perfusion index (PI) was assessed non-invasively by near infrared spectroscopy. A decrease in the postis-chaemic reperfusion capability of the human tibia BM and TA muscle was observed for increasing age i.e., PI increases linearly as a function of age, starting from 30 years, both for BM (0.062 %/year, from -4.185 to -0.967 %/s) and TA muscle (0.046 %/year, from -5.760 to -3.883 %/s). The results define a "normal" baseline and demonstrate the sensitivity of the method to PI changes. The present technique should allow one to investigate physio-pathological effects induced by microgravity on tibia BM blood perfusion.|
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Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
|Research group||Groupe Binzoni Tiziano (radiologie) (234)|
|BINZONI, Tiziano et al. Human tibia bone marrow blood perfusion by non-invasive near infrared spectroscopy: a new tool for studies on microgravity. In: Journal of Gravitational Physiology, 2002, vol. 9, n° 1, p. P183-P184. https://archive-ouverte.unige.ch/unige:91073|