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Scientific article
English

Accumulation of amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles in bone marrow: implications for local stromal cells

ContributorsSchulze, Frank; Gramoun, Azza; Crowe, Lindsey; Dienelt, anke; Akcan, Tugba; Hofmann, Heinrich; Vallée, Jean-Paulorcid; Duda, Georg N; Ode, Andrea
Published inNanomedicine, vol. 10, no. 14, p. 2139-2151
Publication date2015
Abstract

First, it will be investigated if amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles (A-PVA-SPIONs) are suitable for MRI contrast enhancement in bone marrow. Second, the impact of A-PVA-SPION exposure in vivo on the viability and key functions of local bone marrow stromal cells (BMSCs) will be investigated.

Keywords
  • Animals
  • Bone Marrow/metabolism
  • Contrast Media/chemistry/metabolism
  • Ferric Compounds/chemistry
  • Mesenchymal Stromal Cells/metabolism
  • Nanoparticles/chemistry/metabolism
  • Polyvinyl Alcohol/chemistry
  • Rats
Affiliation entities
Research groups
Citation (ISO format)
SCHULZE, Frank et al. Accumulation of amino-polyvinyl alcohol-coated superparamagnetic iron oxide nanoparticles in bone marrow: implications for local stromal cells. In: Nanomedicine, 2015, vol. 10, n° 14, p. 2139–2151. doi: 10.2217/nnm.15.62
Identifiers
Journal ISSN1549-9634
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Update15/03/2023 01:12:23
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