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Levels of interleukin-6 in tears before and after excimer laser treatment

Resan, Mirko
Stanojević, Ivan
Petković, Aleksandra
Vojvodić, Danilo
Published in Vojnosanitetski Pregled. 2015, vol. 72, no. 4, p. 350-355
Abstract Immune response and consequent inflammatory process which originate on ocular surface after a trauma are mediated by cytokines. Photoablation of corneal stroma performed by excimer laser causes surgically induced trauma. Interleukin-6 (IL-6) is mostly known as a proinflammatory cytokine. However, it also has regenerative and anti-inflammatory effects. It is supposed that this cytokine is likely to play a significant role in the process of corneal wound healing response after photoablation of stroma carried out by laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK) methods. The aim of this study was to determine and compare the levels of IL-6 in tears before and after treatment with LASIK and PRK methods.
Keywords AdultComparative Effectiveness ResearchCorneal Injuries/diagnosis/etiology/metabolismFemaleHumansInterleukin-6/analysis/metabolismKeratomileusis, Laser In Situ/adverse effects/methodsMaleMyopia/surgeryPhotorefractive Keratectomy/adverse effects/methodsPostoperative Complications/diagnosis/metabolismTears/metabolismTreatment OutcomeWound Healing/physiology
PMID: 26040181
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RESAN, Mirko et al. Levels of interleukin-6 in tears before and after excimer laser treatment. In: Vojnosanitetski Pregled, 2015, vol. 72, n° 4, p. 350-355.

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Deposited on : 2016-12-16

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