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Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex |
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Published in | BMC genomics. 2015, vol. 16, 337 | |
Abstract | Long non-coding RNAs (lncRNAs) have been defined as mRNA-like transcripts longer than 200 nucleotides that lack significant protein-coding potential, and many of them constitute scaffolds for ribonucleoprotein complexes with critical roles in epigenetic regulation. Various lncRNAs have been implicated in the modulation of chromatin structure, transcriptional and post-transcriptional gene regulation, and regulation of genomic stability in mammals, Caenorhabditis elegans, and Drosophila melanogaster. The purpose of this study is to identify the lncRNA landscape in the malaria vector An. gambiae and assess the evolutionary conservation of lncRNAs and their secondary structures across the Anopheles genus. | |
Keywords | Animals — Anopheles/genetics — Conserved Sequence — Drosophila melanogaster/genetics — Epigenesis, Genetic — Gene Expression Regulation — Humans — Nucleic Acid Conformation — RNA, Long Noncoding/genetics — RNA, Messenger/genetics | |
Identifiers | PMID: 25903279 | |
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Citation (ISO format) | JENKINS, Adam M, WATERHOUSE, Robert, MUSKAVITCH, Marc A T. Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex. In: BMC genomics, 2015, vol. 16, p. 337. doi: 10.1186/s12864-015-1507-3 https://archive-ouverte.unige.ch/unige:90481 |