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Title

Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex
Authors
Jenkins, Adam M
Waterhouse, Robert
Muskavitch, Marc A T
Published in BMC Genomics. 2015, vol. 16, p. 337
Abstract Long non-coding RNAs (lncRNAs) have been defined as mRNA-like transcripts longer than 200 nucleotides that lack significant protein-coding potential, and many of them constitute scaffolds for ribonucleoprotein complexes with critical roles in epigenetic regulation. Various lncRNAs have been implicated in the modulation of chromatin structure, transcriptional and post-transcriptional gene regulation, and regulation of genomic stability in mammals, Caenorhabditis elegans, and Drosophila melanogaster. The purpose of this study is to identify the lncRNA landscape in the malaria vector An. gambiae and assess the evolutionary conservation of lncRNAs and their secondary structures across the Anopheles genus.
Keywords Animals — Anopheles/genetics — Conserved Sequence — Drosophila melanogaster/genetics — Epigenesis, Genetic — Gene Expression Regulation — Humans — Nucleic Acid Conformation — RNA, Long Noncoding/genetics — RNA, Messenger/genetics
Identifiers
PMID: 25903279
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Article (Published version) (2.1 MB) - public document Free access
Structures
Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement
Citation
(ISO format) 		JENKINS, Adam M, WATERHOUSE, Robert, MUSKAVITCH, Marc A T. Long non-coding RNA discovery across the genus anopheles reveals conserved secondary structures within and beyond the Gambiae complex. In: BMC Genomics, 2015, vol. 16, p. 337. https://archive-ouverte.unige.ch/unige:90481

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Deposited on : 2016-12-16

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