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EX-PRESS glaucoma filtration device: Review of clinical experience and comparison with trabeculectomy

Goldberg, Ivan
Fechtner, Robert
Published in Survey of Ophthalmology. 2015, vol. 60, no. 4, p. 327-345
Abstract Glaucoma filtration surgery is performed to reduce intraocular pressure (IOP) in patients for whom maximal tolerable pharmacologic IOP-lowering therapy and/or laser surgery fail to lower IOP sufficiently and/or fail to prevent optic nerve damage or visual field deterioration. For decades, the most widely utilized procedure for glaucoma filtration surgery has been trabeculectomy. Although this approach reliably provides long-term IOP reduction in many patients, the postoperative complication rate is high. This has driven the development of alternative approaches to reduce IOP surgically. The EX-PRESS glaucoma filtration device was developed to mimic IOP control by trabeculectomy and to have a better safety profile. This non-valved, medical-grade stainless steel device diverts aqueous humor from the anterior chamber to an intrascleral space. Despite the widespread use of the EX-PRESS device, only a few studies compare its efficacy and safety with that of trabeculectomy. We analyze available data regarding the safety and efficacy of the EX-PRESS device, particularly in comparison with trabeculectomy.
Keywords Aqueous Humor/physiologyGlaucoma/physiopathology/surgeryGlaucoma Drainage ImplantsHumansIntraocular Pressure/physiologyProsthesis ImplantationTrabeculectomy
PMID: 25910971
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Research group Ophtalmologie expérimentale (925)
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SHAARAWY, Tarek, GOLDBERG, Ivan, FECHTNER, Robert. EX-PRESS glaucoma filtration device: Review of clinical experience and comparison with trabeculectomy. In: Survey of Ophthalmology, 2015, vol. 60, n° 4, p. 327-345. https://archive-ouverte.unige.ch/unige:90475

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Deposited on : 2016-12-16

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