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How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers

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Published in BMC Medical Research Methodology. 2016, vol. 16, p. 89
Abstract There is currently no guidance for selecting a specific difference to be detected in a superiority trial. We explored 3 factors that in our opinion should influence the difference to be detected (type of outcome, patient age group, and presence of treatment side-effects), and 3 that should not (baseline level of risk, logistical difficulties, and cost of treatment).
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PMID: 27473336
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Article (Published version) (670 Kb) - public document Free access
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Research group Epidémiologie clinique (115)
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GAYET-AGERON, Angèle et al. How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers. In: BMC Medical Research Methodology, 2016, vol. 16, p. 89. https://archive-ouverte.unige.ch/unige:90403

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Deposited on : 2016-12-15

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