Correction of prasugrel-related bleeding by prophylactic transfusion of human platelets in a rabbit model

Bonhomme, Fanny; Godier, Anne; Samama, Charles Marc; Lecompte, Thomas Pierre; Fontana, Pierre

doi:10.1111/trf.13765

Scientific article

English

Correction of prasugrel-related bleeding by prophylactic transfusion of human platelets in a rabbit model

ContributorsBonhomme, Fanny; Godier, Anne; Samama, Charles Marc; Lecompte, Thomas Pierre; Fontana, Pierre

Published inTransfusion, vol. 56, no. 10, p. 2618-2626

Publication date2016

Abstract

Prasugrel provides rapid and intense inhibition of platelet aggregation combined with an increased risk of bleeding. We evaluated the efficacy and safety of platelet transfusion to reduce blood loss after a prasugrel loading dose in a rabbit model.

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Citation (ISO format)

BONHOMME, Fanny et al. Correction of prasugrel-related bleeding by prophylactic transfusion of human platelets in a rabbit model. In: Transfusion, 2016, vol. 56, n° 10, p. 2618–2626. doi: 10.1111/trf.13765

Article (Published version)

Identifiers

PID : unige:90308
DOI : 10.1111/trf.13765
PMID : 27546107

Journal ISSN0041-1132

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Creation02/12/2016 18:16:00

First validation02/12/2016 18:16:00

Update time15/03/2023 02:09:58

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Correction of prasugrel-related bleeding by prophylactic transfusion of human platelets in a rabbit model

Prasugrel provides rapid and intense inhibition of platelet aggregation combined with an increased risk of bleeding. We evaluated the efficacy and safety of platelet transfusion to reduce blood loss after a prasugrel loading dose in a rabbit model.

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