Gadoxetate-enhanced MR imaging and compartmental modelling to assess hepatocyte bidirectional transport function in rats with advanced liver fibrosis

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Title		Gadoxetate-enhanced MR imaging and compartmental modelling to assess hepatocyte bidirectional transport function in rats with advanced liver fibrosis
Authors		Giraudeau, Céline Leporq, Benjamin Doblas, Sabrina Lagadec, Matthieu Pastor, Catherine Daire, Jean-Luc Van Beers, Bernard E
Published in		European Radiology. 2017, vol. 27, no. 5, p. 1804-1811
Abstract		Changes in the expression of hepatocyte membrane transporters in advanced fibrosis decrease the hepatic transport function of organic anions. The aim of our study was to assess if these changes can be evaluated with pharmacokinetic analysis of the hepatobiliary transport of the MR contrast agent gadoxetate.
Identifiers		DOI: 10.1007/s00330-016-4536-7 PMID: 27553933
Full text		Article (Author postprint) (794 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research group		Pharmacologie et imagerie du foie (664)
Citation (ISO format)		GIRAUDEAU, Céline et al. Gadoxetate-enhanced MR imaging and compartmental modelling to assess hepatocyte bidirectional transport function in rats with advanced liver fibrosis. In: European Radiology, 2017, vol. 27, n° 5, p. 1804-1811. https://archive-ouverte.unige.ch/unige:90293

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Deposited on : 2016-12-13

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