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Title

Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

Authors
Morrison, Alanna C
Bis, Joshua C
Hwang, Shih-Jen
Lumley, Thomas
Rice, Kenneth
Muzny, Donna
Gibbs, Richard A
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Published in PLOS ONE. 2014, vol. 9, no. 10, p. e109155
Abstract Genome-wide association studies (GWAS) identified multiple loci for blood pressure (BP) and hypertension. Six genes--ATP2B1, CACNB2, CYP17A1, JAG1, PLEKHA7, and SH2B3--were evaluated for sequence variation with large effects on systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), and mean arterial pressure (MAP).
Keywords Aging/geneticsBlood Pressure/geneticsCohort StudiesHeart/physiologyHumansSequence Analysis
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PMID: 25275628
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Research group Traits génétiques complexes (901)
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MORRISON, Alanna C et al. Sequence analysis of six blood pressure candidate regions in 4,178 individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study. In: PLOS ONE, 2014, vol. 9, n° 10, p. e109155. https://archive-ouverte.unige.ch/unige:90152

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Deposited on : 2016-12-08

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