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English

TSS-EMOTE, a refined protocol for a more complete and less biased global mapping of transcription start sites in bacterial pathogens

Contributors

Prados, Julien; Linder, Patrick; Redder, Peter

Published in

BMC genomics, vol. 17, no. 1, 849

Publication date

2016

Abstract

Bacteria rely on efficient gene regulatory mechanisms to switch between genetic programs when they are facing new environments. Although this regulation can occur at many different levels, one of the key steps is the initiation of transcription. Identification of the first nucleotide transcribed by the RNA polymerase is therefore essential to understand the underlying regulatory processes, since this provides insight on promoter strength and binding sites for transcriptional regulators, and additionally reveals the exact 5' untranslated region of the transcripts, which often contains elements that regulate translation.

UNIGE affiliation entities

UNIGE research groups

Citation (ISO format)

PRADOS, Julien, LINDER, Patrick, REDDER, Peter. TSS-EMOTE, a refined protocol for a more complete and less biased global mapping of transcription start sites in bacterial pathogens. In: BMC genomics, 2016, vol. 17, n° 1, p. 849. doi: 10.1186/s12864-016-3211-3

Main files (1)

Article (Published version)

Identifiers

Journal ISSN

1471-2164
634views
620downloads

Technical informations

Creation

07/11/2016 12:11:00

First validation

07/11/2016 12:11:00

Update

15/03/2023 01:08:04

Status update

15/03/2023 01:08:03

Last indexation

11/02/2025 09:34:10
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