Neurophysiologic evidence for a central sensitization in patients with fibromyalgia

Desmeules, Jules Alexandre; Cedraschi, Christine; Rapiti Aylward, Elisabetta; Baumgartner, E; Finckh, Axel; Cohen, Paul; Dayer, Pierre; Vischer, T L

doi:10.1002/art.10893

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Title		Neurophysiologic evidence for a central sensitization in patients with fibromyalgia
Authors		Desmeules, Jules Alexandre Cedraschi, Christine Rapiti Aylward, Elisabetta Baumgartner, E Finckh, Axel Cohen, Paul Dayer, Pierre Vischer, T L
Published in		Arthritis and Rheumatism. 2003, vol. 48, no. 5, p. 1420-1429
Abstract		To determine whether abnormalities of peripheral and central nociceptive sensory input processing exist outside areas of spontaneous pain in patients with fibromyalgia (FM) as compared with controls, by using quantitative sensory testing (QST) and a neurophysiologic paradigm independent from subjective reports.
Keywords		Female — Fibromyalgia/complications/physiopathology/therapy — Humans — Hyperalgesia/etiology/physiopathology — Male — Middle Aged — Nociceptors/physiopathology — Outpatients — Pain/physiopathology — Pain Measurement — Pain Threshold/physiology — Quality of Life — Reflex/physiology — Self Care — Sickness Impact Profile — Surveys and Questionnaires
Identifiers		DOI: 10.1002/art.10893 PMID: 12746916
Full text		Article (Published version) (109 Kb) - Free access
Structures		Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale / Registre genevois des tumeurs
Research groups		Aspects psychosociaux des maladies chroniques (247) Groupe Bouchardy Magnin Christine (Registre genevois des tumeurs) (532) Groupe Desmeules Jules (pharmacologie/toxicologie) (567) Mécanisme de l'inflammation articulaire (44) Epidémiologie des tumeurs (1017)
Project		FNS: 3200-056028.98
Citation (ISO format)		DESMEULES, Jules Alexandre et al. Neurophysiologic evidence for a central sensitization in patients with fibromyalgia. In: Arthritis and Rheumatism, 2003, vol. 48, n° 5, p. 1420-1429. doi: 10.1002/art.10893 https://archive-ouverte.unige.ch/unige:90111