Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait

Fleury, Vanessa; Pollak, Pierre; Gere, Julien; Tommasi, Giorgio; Romito, Luigi; Combescure, Christophe; Bardinet, Eric; Chabardes, Stephan; Momjian, Shahan Marc; Krainik, Alexandre; Burkhard, Pierre; Yelnik, Jérôme; Krack, Paul

doi:10.1002/mds.26545

Scientific article

English

Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait

ContributorsFleury, Vanessa; Pollak, Pierre; Gere, Julien; Tommasi, Giorgio; Romito, Luigi; Combescure, Christophe

; Bardinet, Eric; Chabardes, Stephan; Momjian, Shahan Marc; Krainik, Alexandre; Burkhard, Pierre

; Yelnik, Jérôme; Krack, Paul

Published inMovement disorders, vol. 31, no. 9, p. 1389-1397

Publication date2016

Abstract

Gait and akinesia deterioration in PD patients during the immediate postoperative period of DBS has been directly related to stimulation in the subthalamic region. The underlying mechanisms remain poorly understood. The aim of the present study was to clinically and anatomically describe this side effect.

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Citation (ISO format)

FLEURY, Vanessa et al. Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait. In: Movement disorders, 2016, vol. 31, n° 9, p. 1389–1397. doi: 10.1002/mds.26545

Article (Published version)

Identifiers

PID : unige:89996
DOI : 10.1002/mds.26545
PMID : 26887333

Journal ISSN0885-3185

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Subthalamic stimulation may inhibit the beneficial effects of levodopa on akinesia and gait

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