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Title

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Authors
Hou, Liping
Heilbronner, Urs
Degenhardt, Franziska
Adli, Mazda
Akiyama, Kazufumi
Akula, Nirmala
Ardau, Raffaella
Arias, Bárbara
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Published in The Lancet. 2016, vol. 387, no. 10023, p. 1085-1093
Abstract Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers of treatment response have been reproducibly identified.
Keywords Bipolar Disorder/drug therapy/geneticsFemaleGenetic VariationGenome-Wide Association StudyGenotypeGlial Cell Line-Derived Neurotrophic Factor Receptors/geneticsHumansLithium Compounds/therapeutic useMaleMiddle AgedPhenotypePolymorphism, Single Nucleotide/geneticsProspective StudiesTreatment Outcome
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PMID: 26806518
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Structures
Research groups Thérapeutiques des Troubles de l'Humeur et Anxieux (689)
Groupe Dayer Alexandre (Formation du circuit cortical) (875)
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HOU, Liping et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. In: The Lancet, 2016, vol. 387, n° 10023, p. 1085-1093. https://archive-ouverte.unige.ch/unige:89914

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Deposited on : 2016-12-06

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