AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties
Published inThe Journal of pharmacology and experimental therapeutics, vol. 310, no. 1, p. 25-32
Publication date2004
Abstract
Keywords
- Acetonitriles/pharmacology/therapeutic use
- Animals
- Benzothiazoles
- Brain Ischemia/complications/etiology/prevention & control
- Disease Models, Animal
- Gerbillinae
- JNK Mitogen-Activated Protein Kinases
- Lipopolysaccharides/pharmacology
- Mice
- Mice, Inbred C3H
- Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism
- Neuroprotective Agents/pharmacology/therapeutic use
- Phosphorylation/drug effects
- Rats
- Rats, Wistar
- Thiazoles/pharmacology/therapeutic use
- Tumor Necrosis Factor-alpha/metabolism
Affiliation Not a UNIGE publication
Citation (ISO format)
CARBONI, Sonia et al. AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties. In: The Journal of pharmacology and experimental therapeutics, 2004, vol. 310, n° 1, p. 25–32. doi: 10.1124/jpet.103.064246
Main files (1)
Article (Published version)
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Identifiers
- PID : unige:89903
- DOI : 10.1124/jpet.103.064246
- PMID : 14988419
ISSN of the journal0022-3565