Hippocampal and amygdalar local structural differences in elderly patients with schizophrenia

Prestia, Annapaola; Cavedo, Enrica; Boccardi, Marina; Muscio, Cristina; Adorni, Andrea; Geroldi, Cristina; Bonetti, Matteo; Thompson, Paul M; Frisoni, Giovanni

doi:10.1016/j.jagp.2014.01.006

Scientific article

English

Hippocampal and amygdalar local structural differences in elderly patients with schizophrenia

ContributorsPrestia, Annapaola; Cavedo, Enrica; Boccardi, Marina; Muscio, Cristina; Adorni, Andrea; Geroldi, Cristina; Bonetti, Matteo; Thompson, Paul M; Frisoni, Giovanni

Published inThe American journal of geriatric psychiatry, vol. 23, no. 1, p. 47-58

Publication date2015

Abstract

Morphological abnormalities have been reported for the hippocampi and amygdalae in young schizophrenia patients, but very little is known about the pattern of abnormalities in elderly schizophrenia patients. Here we investigated local structural differences in the hippocampi and amygdalae of elderly schizophrenia patients compared with healthy elderly subjects. We also related these differences to clinical symptom severity.

Keywords

Aged
Aged, 80 and over
Aging/pathology/physiology
Amygdala/pathology/physiopathology
Female
Hippocampus/pathology/physiopathology
Humans
Magnetic Resonance Imaging/methods
Male
Middle Aged
Schizophrenia/pathology/physiopathology

Affiliation

Faculté de médecine / Section de médecine clinique / Département de psychiatrie

Research group

Troubles de mémoire et maladie d'Alzeimer (935)

Citation (ISO format)

PRESTIA, Annapaola et al. Hippocampal and amygdalar local structural differences in elderly patients with schizophrenia. In: The American journal of geriatric psychiatry, 2015, vol. 23, n° 1, p. 47–58. doi: 10.1016/j.jagp.2014.01.006

Article (Accepted version)

Identifiers

PID : unige:89735
DOI : 10.1016/j.jagp.2014.01.006
PMID : 24534522

ISSN of the journal1064-7481

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Hippocampal and amygdalar local structural differences in elderly patients with schizophrenia

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